While trying to flash the klipper firmware to an Bigtreetech EBB36, i ran into the following error:

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23:29:04 : Erasing memory corresponding to segment 0:
23:29:04 : Not flash Memory : No erase done
23:29:04 : File segment @0x08000000 is not 255-bytes aligned. It will be aligned to @0x07FFFFF8
23:29:04 : Download in Progress:
23:29:05 : Error: failed to download Segment[0]
23:29:05 : Error: failed to download the File

After fiddeling around a bit i finally stumbled across two solutions.

Use Canboot to flash an intermediate firmware

This  failed for me but might a possible path to fix it

Use an older version of the STM32CubeProgrammer

I used version 2.10 of the STM32CubeProgrammer  which solved the case for me at least.